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HBX 41108
CAS No. 924296-39-9
HBX 41108( HBX-41108 )
Catalog No. M27424 CAS No. 924296-39-9
HBx 41108 is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBx 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 61 | Get Quote |
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| 5MG | 102 | Get Quote |
|
| 10MG | 170 | Get Quote |
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| 25MG | 402 | Get Quote |
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| 50MG | 593 | Get Quote |
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| 100MG | 845 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameHBX 41108
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NoteResearch use only, not for human use.
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Brief DescriptionHBx 41108 is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBx 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.
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DescriptionHBx 41108 is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBx 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.
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In Vitro——
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In Vivo——
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SynonymsHBX-41108
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PathwayProteasome/Ubiquitin
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TargetDUB
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RecptorBax|Bcl-2|Caspase-3
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Research Area——
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Indication——
Chemical Information
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CAS Number924296-39-9
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Formula Weight266.64
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Molecular FormulaC13H3ClN4O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (937.59 mM)
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SMILESClc1ccc-2c(c1)C(=O)c1nc(C#N)c(nc-21)C#N
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zhou D, et al. Antiproliferative steroidal glycosides from rhizomes of Polygonatum sibiricum. Phytochemistry. 2019;164:172-183.
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